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Pronounced: IN-deh-ride
Generic ingredients: Inderal (Propranolol hydrochloride), Hydrochlorothiazide
Other brand name: Inderide LA

Why is this drug prescribed: Inderide is used in the treatment of high blood pressure. It combines a beta blocker (Inderal) with a thiazide diuretic (hydrochlorothiazide). Beta blockers decrease the force and rate of heart contractions, thus lowering blood pressure. Diuretics help your body produce and eliminate more urine, which also helps lower blood pressure.

Most important fact about this drug: You must take Inderide regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Inderide; and you must continue taking it even if you are feeling well. Inderide does not cure high blood pressure; it merely keeps it under control.

How should you take this medication: Take Inderide exactly as prescribed, even if your symptoms have disappeared. Try not to miss any doses. If this medication is not taken regularly, your condition may worsen. --If you miss a dose... Take it as soon as you remember. If the next dose is within 8 hours, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time. --Storage instructions... Store at room temperature in a tightly closed container, protected from moisture, freezing, and excessive heat.

What side effects may occur: Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Inderide. Side effects may include: Allergic reactions (including fever, rash, aching and sore throat), anemia, blood disorders, blurred vision, constipation, congestive heart failure, cramps, decreased mental clarity, depression, diarrhea, difficulty breathing, difficulty sleeping, disorientation, dizziness, dizziness when standing, dry eyes, emotional changeability, exhaustion, fatigue, hair loss, hallucinations, headache, high blood sugar, hives, increased skin sensitivity to sunlight, inflammation of the large intestine or the pancreas, inflammation of the salivary glands, light-headedness, loss of appetite, low blood pressure, lupus erythematosus (a connective tissue disease), male impotence, muscle spasms, nausea, restlessness, short-term memory loss, slow heartbeat, stomach irritation, sugar in the urine, tingling or pins and needles, upset stomach, vertigo, visual disturbances, vivid dreams, vomiting, weakness, wheezing, yellow eyes and skin

Why should this drug not be prescribed: If you have inadequate blood supply to the circulatory system (cardiogenic shock), certain types of irregular heartbeat, slow heartbeat, bronchial asthma, or congestive heart failure, you should not take this medication. Do not take Inderide if you are unable to urinate or if you are sensitive to or have ever had an allergic reaction to any of its ingredients or to sulfa drugs.

Special warnings about this medication: Inderide should not be stopped suddenly. This can cause chest pain and even heart attack. Dosage should be gradually reduced. Diuretics can cause your body to lose too much potassium. Signs of an excessively low potassium level include muscle weakness and rapid or irregular heartbeat. To boost your potassium level, your doctor may recommend eating potassium-rich foods or taking a potassium supplement. If you suffer from asthma, seasonal allergies or other bronchial conditions, or kidney or liver disease, your doctor will prescribe this medication with caution. This medication may mask the symptoms of low blood sugar or alter blood sugar levels. If you are diabetic, discuss this with your doctor. If you have a history of allergies or bronchial asthma, you are more likely to have an allergic reaction to Inderide. Inderide may interfere with the screening test for glaucoma (excessive pressure in the eyes) and pressure within the eyes may increase when the medication is stopped. Notify your doctor or dentist that you are taking Inderide if you have a medical emergency, and before you have surgery or dental treatment.

Possible food and drug interactions when taking this medication: If Inderide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Inderide with the following: ACTH (adrenocorticotropic hormone) Alcohol Aluminum hydroxide gel (Amphojel) Antipyrine (Auralgan) Calcium-blocking blood pressure drugs such as Calan, Cardizem, and Procardia XL Certain blood pressure medications such as Diupres and Ser-Ap-Es Chlorpromazine (Thorazine) Cimetidine (Tagamet) Corticosteroids such as prednisone Digitalis (Lanoxin) Epinephrine (EpiPen) Haloperidol (Haldol) Insulin Lidocaine (Xylocaine) Nonsteroidal anti-inflammatory drugs such as Motrin Norepinephrine (Levophed) Oral diabetes drugs such as Micronase Phenobarbitone Phenytoin (Dilantin) Rifampin (Rifadin) Theophylline (Theo-Dur) Thyroid medications such as Synthroid

Special information if you are pregnant or breastfeeding: The effects of Inderide during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Inderide appears in breast milk and could affect a nursing infant. If Inderide is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Recommended dosage: ADULTS: Your doctor will tailor your dosage according to your response to Inderide's main ingredients. The usual dose is one Inderide tablet, 2 times per day. Your doctor may use this medication in combination with other high blood pressure drugs to achieve the desired effect. This drug is also available in a sustained-release formulation, called Inderide LA, for once-a-day dosing. CHILDREN: The safety and effectiveness of this drug in children have not been established. OLDER ADULTS: Your doctor will adjust your dosage with extra caution.

Overdosage: Any medication taken in excess can have severe consequences. If you suspect an overdose, seek medical attention immediately. Symptoms of Inderide overdose may include: Coma, extremely slow heartbeat, heart failure, increased urination, irritation and overactivity of the stomach and intestines, low blood pressure, sluggishness, stupor, wheezing

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