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Pronounced: toe-LEK-tin
Generic name: Tolmetin sodium

Why is this drug prescribed: Tolectin is a nonsteroidal anti-inflammatory drug used to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis (the most common form of arthritis). It is used for both acute episodes and long-term treatment. It is also used to treat juvenile rheumatoid arthritis.

Most important fact about this drug: You should have frequent checkups with your doctor if you take Tolectin regularly. Ulcers or internal bleeding can occur without warning.

How should you take this medication: If Tolectin upsets your stomach, it may be taken with food or an antacid, and with a full glass of water. It may also help to prevent upset if you avoid lying down for 20 to 30 minutes after taking the drug. Take this medication exactly as prescribed by your doctor. --If you miss a dose... Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time. --Storage instructions... Store at room temperature in a tightly closed container, away from light.

What side effects may occur: Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Tolectin. More common side effects may include: Abdominal pain, change in weight, diarrhea, dizziness, gas, headache, heartburn, high blood pressure, indigestion, nausea, stomach and intestinal upset, swelling due to fluid retention, vomiting, weakness Less common or rare side effects may include: Anemia, blood in urine, chest pain, congestive heart failure, constipation, depression, drowsiness, fever, hepatitis, hives, inflammation of the mouth or tongue, kidney failure, painful urination, peptic ulcer, purple or reddish spots on skin, ringing in the ears, severe allergic reactions, skin irritation, stomach inflammation, stomach or intestinal bleeding, urinary tract infection, visual disturbances, yellow eyes or skin

Why should this drug not be prescribed: If you are sensitive to or have ever had an allergic reaction to Tolectin, aspirin, or other nonsteroidal anti-inflammatory drugs, or if you have had asthma, hives, or nasal inflammation caused by aspirin or other nonsteroidal anti-inflammatory drugs, you should not take this medication. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about this medication: Tolectin can cause kidney problems, especially if you are elderly, suffer from heart failure or liver disease, or take diuretics. This drug can also affect the liver. If you develop symptoms such as yellow skin and eyes, notify your doctor. You should be taken off Tolectin. Do not take aspirin or any other anti-inflammatory medications while taking Tolectin unless your doctor tells you to do so. Tolectin can cause visual disturbances. If you experience a change in your vision, inform your doctor. Tolectin prolongs bleeding time. If you are taking blood-thinning medication, this drug should be taken with caution. This drug can increase water retention. Use with caution if you have heart disease or high blood pressure. Tolectin causes some people to become drowsy or less alert. If it has this effect on you, driving or operating dangerous machinery or participating in any hazardous activity that requires full mental alertness is not recommended.

Possible food and drug interactions when taking this medication: If Tolectin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Tolectin with the following: Aspirin Blood thinners such as Coumadin Carteolol (Cartrol) Diuretics such as Lasix Glyburide (Micronase) Lithium (Lithonate) Methotrexate

Special information if you are pregnant or breastfeeding: The effects of Tolectin during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Tolectin appears in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Recommended dosage: ADULTS: Rheumatoid Arthritis or Osteoarthritis The starting dosage is usually 1,200 milligrams a day divided into 3 doses of 400 milligrams each. Take 1 dose when you wake up and 1 at bedtime, and 1 sometime in between. Your doctor may adjust the dosage after 1 to 2 weeks. Most people will take a total daily dosage of 600 to 1,800 milligrams usually divided into 3 doses. You should see the benefits of Tolectin in a few days to a week. CHILDREN: The starting dose for children 2 years and older is usually a total of 20 milligrams per 2.2 pounds of body weight per day, divided into 3 or 4 smaller doses. Your doctor will advise you on use in children. The usual dose ranges from 15 to 30 milligrams per 2.2 pounds per day. The safety and effectiveness of Tolectin have not been established in children under 2 years of age.

Overdosage: Although no specific information is available, any medication taken in excess can have serious consequences. If you suspect an overdose of Tolectin, seek medical attention immediately.

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