Information on Tablets A-Z
Generic name: Linezolid
Why is this drug prescribed: Zyvox is a member of a new class of antibiotics called oxazolidinones. It is used to treat certain types of pneumonia, some forms of skin infection, and infections involving certain strains of a germ called Enterococcus faecium.
Most important fact about this drug: Antibiotic treatment can cause a type of diarrhea that, in rare cases, becomes extremely severe. If you develop diarrhea after starting Zyvox, be sure to notify your doctor immediately.
How should you take this medication: Zyvox should be taken twice a day, every 12 hours, until the prescription is finished. Do not stop taking the medicine when you start to feel better. If you discontinue it too soon, surviving germs may cause a relapse. Zyvox may be taken with or without food. If you are taking the liquid formulation of Zyvox, gently mix it before each use by turning the bottle upside down and upright 3 to 5 times. Do not shake the bottle. --If you miss a dose... Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time. --Storage instructions... Both Zyvox tablets and Zyvox liquid can be stored at room temperature. Keep the bottles tightly closed and protect from light and moisture. The liquid formulation should be used within 21 days.
What side effects may occur: Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zyvox. More common side effects may include: Diarrhea, headache, nausea, vomiting Less common and rare side effects may include: Changes in taste, constipation, dizziness, fever, fungal infection of the mouth, insomnia, itching, rash, tongue discoloration, vaginal infection
Why should this drug not be prescribed: If Zyvox gives you an allergic reaction, you won't be able to use it.
Special warnings about this medication: If you need to take Zyvox for more than two weeks, your doctor will perform blood tests to check for blood abnormalities. Blood tests are also needed if you tend to bleed easily or are taking medications that increase your chance of bleeding. Let the doctor know if you have high blood pressure. Zyvox has not been tested under these conditions. If you have a condition called phenylketonuria and must avoid the amino acid phenylalanine, it's important to know that the liquid formulation of Zyvox contains this substance. Zyvox is not recommended for children.
Possible food and drug interactions when taking this medication: If Zyvox is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zyvox with the following: Serotonin-boosting antidepressants such as Paxil, Prozac, and Zoloft, as well as other antidepressants such as Elavil and Tofranil Decongestants such as Sudafed and Entex Over-the-counter cold medicines and cough syrups that contain pseudoephedrine While taking Zyvox, it's important to avoid eating large amounts of foods that contain a chemical called "tyramine." Food products high in tyramine include aged cheese, fermented or air-dried meats such as dry sausage, sauerkraut, soy sauce, red wine, tap beers, and any protein-rich food that has been improperly refrigerated.
Special information if you are pregnant or breastfeeding: Zyvox has not been studied in pregnant women or nursing mothers. Because the possibility of harm to the developing baby has not been ruled out, Zyvox should be used during pregnancy only if the potential benefit outweighs the possible risk. If you wish to breastfeed your infant, discuss your treatment options with your doctor.
Recommended dosage: Pneumonia and Complicated Skin Infections The usual dosage is 600 milligrams every 12 hours for 10 to 14 days. Uncomplicated Skin Infections The usual dosage is 400 milligrams every 12 hours for 10 to 14 days. Enterococcus faecium Infections The usual dosage is 600 milligrams every 12 hours for 14 to 28 days.
Overdosage: Little is known about the effects of a Zyvox overdose. However, any medication taken in excess can have serious consequences, so if you suspect an overdose, seek medical attention immediately.